Research Paper Volume 15, Issue 13 pp 6117—6134

Confirmation of the predictive function of cuproptosis-related gene FDX1 in clear cell renal carcinoma using qRT-PCR and western blotting

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Figure 6. Function and pathway analyses of FDX1 related genes. (A) Circle graph of co-expression genes with FDX1 for GO functional analysis. Red represents a positive correlation and green represents a negative correlation. (B, C) Histogram and bubble diagram of GO. (D) Circle graph of GO. The first circle indicates 18 GO terms, with the coordinate scale of the gene number displayed outside the circle. The second circle shows the number of GO terms and Q values in the background gene. The third circle illustrates GO term number of associated genes. The fourth circle displays the abundance factor values for each GO term associated gene. (E, F) Histogram and bubble diagram in KEGG pathway analysis. (G) Pathway diagram of Oxidative Phosphorylation. Red background represents key genes with high expression.