Figure 1. (A) The 5 essential drug components of XBJ: Paeoniae Radix Rubra, Chuanxiong Rhizuma, Angelicae Sinensis Radix, Salviae Militiorrhizae Radix et Rhizuma, and Carthami Flos. (B) Graphical Abstract: a guideline of the entire procedure for developing a rat sepsis model and therapeutic administration. (C) The survival rate of XBJ for SIMI was evaluated by the Kaplan-Meier method followed by the log rank test within 7 days.