Figure 2 — DNMT1 regulates polarization of macrophage-induced intervertebral disc degeneration by modulating SIRT6 expression and promoting pyroptosis in vivo

Research Paper|Volume 15, Issue 10|pp. 4288–4303

DNMT1 regulates polarization of macrophage-induced intervertebral disc degeneration by modulating SIRT6 expression and promoting pyroptosis in vivo

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Figure 2.Macrophage M1/M2 markers in nucleus pulposus tissue homogenate determined by ELISA after 12 weeks of surgery. Data are presented as the mean and SD. M1 macrophage specific markers: iNOS and TNF-α, and M2 macrophage-specific markers: CD163, Arg-1, MR.