Research Paper Volume 15, Issue 9 pp 3715—3737

Figure 5. Inflammation marker analysis in the cortex (Cor) and hippocampus (Hip) of wild-type (WT) and AD mice. Immunofluorescence analysis of interleukin (IL)-1β (A), IL-6 (B), and tumor necrosis factor (TNF)-α (C) in the Cor and Hip of WT mice (a), AD mice (b), plasmin-activated water (PAW)-fed (AD+PAW) mice (c), and fecal microbiota transplantation (FMT) AD mice (AD+FMT) (d). Statistical results were analyzed in the Cor (e) and Hip (f) from (A), (B), and (C). (D) Protein concentrations of IL-1β (a, b), IL-6 (c, d), and TNF-α (e, f) from the Cor and Hip were measured by ELISA of WT, WT+PAW, WT+FMT, AD, AD+PAW, and AD+FMT mice. All results were analyzed by ANOVA with a post hoc analysis. (^*p < 0.05, ^**p < 0.01, ^***p < 0.001). Mean values ± standard deviation of mean (SD) was shown.