Research Paper Volume 15, Issue 9 pp 3644—3677
FAM46C-mediated tumor heterogeneity predicts extramedullary metastasis and poorer survival in multiple myeloma
Figure 5. The expression of FAM46C is an independent prognostic factor in multiple myeloma. (A) Cox regression analysis identified FAM46C expression (cut off FAM46C ≥ 13.6) as an independent prognostic factor in 559 multiple myeloma patients. OS, overall survival; EPS, progress free survival. Abbreviations: β2-MG: β2 microglobulin; ALB: serum albumin; HR: hazard ratio; CI: confidence interval. (B) Lower transcriptome expression level in FAM46C-low group compared with FAM46C-high group in 559 multiple myeloma patients. P = 0.0043, unpaired t test, two sided (cut off FAM46C ≥ 13.6).