Research Paper Volume 15, Issue 9 pp 3635—3643
TIMP2 facilitates CIRI through activating NLRP3-mediated pyroptosis
Figure 2. TIMP2 aggravates brain tissue injury in CIRI mice. QPCR is used to measure the expression of TIMP2 in the control, I/R, and I/R+TIMP2 groups. The expression of TIMP2 is significantly higher in the I/R group and the I/R+TIMP2 group than that in the control group. In addition, the expression of TIMP2 is significantly higher in the I/R+TIMP2 group than that in the I/R group. **P < 0.01, *P < 0.05.