Research Paper Volume 15, Issue 14 pp 6721—6735
Th1 promotes M1 polarization of intestinal macrophages to regulate colitis-related mucosal barrier damage
Figure 7. Th1 cells promoted M1 polarization of intestinal macrophages. (A, B) FCM (n=3). The proportion of F4/80+CD11b+ cells in Th1 cells evidently increased, and the difference was significant compared with Control group, *P<0.05. (C) ELISA (n=3). The levels of TNF-α, IL-6 and IL-1β markedly increased, and the differences were significant compared with Control group, *P<0.05. (D, E) Protein detection results (n=3). The p-STAT3 level in Th1 cells was markedly up-regulated, and the difference was significant compared with Control group, *P<0.05.