Research Paper Volume 15, Issue 14 pp 6721—6735
Th1 promotes M1 polarization of intestinal macrophages to regulate colitis-related mucosal barrier damage
Figure 6. Changes of intestinal histopathology after the scavenging of mouse macrophages. (A) H&E (n=5). In DSS+Th1+CCL group, the tissue exhibited obvious inflammation and edema, which were markedly alleviated relative to DSS+Th1 group. (B) IHC (n=5). The levels of ZO1 and Occludin proteins in DSS+Th1+CCL group were markedly higher than those in DSS+Th1 group.