Figure 6. Relative expressions of angiogenesis-associated proteins in each group. (A, B) Relative protein expressions of VEGF, COX-2 and HIF-1α in ESM1-NC group, ESM1-mimic group, ESM1-NC + PI3K inhibitor group and ESM1-mimic + PI3K inhibitor group. (C, D) Statistics for VEGF, COX-2 and HIF-1α protein expressions. *p < 0.05 and **p < 0.01 vs. ESM1-NC group.