Research Paper Volume 15, Issue 1 pp 261—275
The protective effect of luteolin on the depression-related dry eye disorder through Sirt1/NF-κB/NLRP3 pathway
Figure 5. Role of Sirt1 in the reduction of CUMS-induced depressive behavior by luteolin. (A) Sucrose preference rate of mice was determined by SPT. (B) The immobility time of mice was measured by TST. (C) Western Blot analysis of the expression of AC-NF-κB, NF-κB, GSDMD-N and GSDMD protein in hippocampal tissue. (D) Nisi staining of mice treated with EX-527. Data were analyzed by means ± SEM. Compared with blank group, ##P < 0.01; Comparison with model group *P < 0.05, **P < 0.01, n = 9.