Research Paper Volume 15, Issue 1 pp 230—245
Increased expression of GPX4 promotes the tumorigenesis of thyroid cancer by inhibiting ferroptosis and predicts poor clinical outcomes
Figure 6. Knockdown of GPX4 activates ferroptosis in thyroid cancer cells. Relative iron (A), GSH (B) and MDA (C) contents in FTC133 cells transfected with NC siRNA/siGPX4 after treatment with erastin. (D) Detection of lipid ROS levels in FTC133 cells transfected with NC siRNA/siGPX4 after treatment with erastin; scale bars: 50 μm. *p<0.05, **p<0.01.