Research Paper Volume 14, Issue 24 pp 10050—10066

Figure 3. SGOL2 deletion inhibited prostate cancer proliferation and migration. (A) Cell proliferation was measured by CCK8 assay at 24h, 48h, 72h, and 96h after transfecting with shSGOL2-1, shSGOL2-3 and the control group for 48h. (B) Apoptosis of prostate cancer was performed after knocking down SGOL2 (shRNA-3) for 48h. (C) Wound-healing assay presented the metastatic ability in shSGOL2-3 and shCtrl groups. (D) Cell cycle assay revealed the proportion of cells in different cell phases after transfection. (E) Transwell assay presented the migratory cells between shSGOL2-3 and the control group. *, P<0.05; **, P<001; ***, P<0.001.