Research Paper Volume 14, Issue 24 pp 10027—10049
High MCM8 expression correlates with unfavorable prognosis and induces immune cell infiltration in hepatocellular carcinoma
Figure 2. MCM8 mRNA levels in HCC and adjacent normal liver tissues and its prognostic value. (A–C) MCM8 mRNA was up-regulated in HCC tissues in TCGA (A), GSE54236 (B) and GSE76426 (C) datasets. (D) ROC curve shows the diagnostic significance of MCM8 mRNA for HCC in TCGA and GEO databases. (E, F) The MCM8 mRNA levels gradually increased with the progression of tumor stage (E) and grade (F). (G–J) High MCM8 expression was correlated with poor OS (G), RFS (H), PFS (I) and DSS (J) in HCC. (K) Higher MCM8 mRNA level was one of the independent risk factors for OS in TCGA database.