Figure 3. Interaction between biological age and HIV status on the posterior cingulate theta response and the medial prefrontal cortex alpha response. (A) The brain image (middle) represents the voxel-wise interaction between biological age and HIV status (i.e., people with HIV vs. seronegative controls) in oscillatory theta power in the left posterior cingulate. (B) The brain image (middle) represents the voxel-wise interaction between biological age and HIV status in oscillatory alpha power in the right medial prefrontal cortex. Peak voxel power values were extracted from both clusters depicted in these images and plotted as a function of biological age by HIV status to visualize the differing relationships between biological age and oscillatory neural activity. *p < 0.05.