Research Paper Volume 14, Issue 24 pp 9890—9907
Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF
Figure 8. Effects of exosomal miR-584-5p on the expression of related genes and proteins in HMC3 cells. The mRNA expression of BDNF (A), TrkB (B), IL-1β (C) and Caspase 3 (D) in the HMC3 cells after transfected with exosomes and miR-584-5p mimics using RT-qPCR. (E) The protein bands visualized by western blot. The protein expression levels of BDNF (F), IL-1β (G) and p-TrkB (H). *: P < 0.05, compared with the control group. #: P < 0.05, compared with the Exos group.