Figure 2. Transition probability matrices by age group from baseline to the 12-year follow-up (N=3,363). Sexagenarians: Unspecific (Unsp); Cardiovascular and anemia (CV and Anemia); Cardio-metabolic (Cardio-Meta) and Psychiatric-endocrine and sensorial (Psy-Endoc and Sens). Septuagenarians: Unspecific (Unsp); Cardiovascular and diabetes (CV and Diab); Neuro-vascular and skin-sensorial (NeuroVasc and Skin); and Neuro-psychiatric and sensorial (NeuroPsy and Sens). Octogenarians and beyond: Unspecific (Unsp); Respiratory-circulatory and skin (Resp-Circula and Skin); Cardio-respiratory and neurological (CardioResp and Neuro); and Neuro-sensorial (Neuro-Sens).