Figure 2 — ESR1 dysfunction triggers neuroinflammation as a critical upstream causative factor of the Alzheimer’s disease process

Research Paper|Volume 14, Issue 21|pp. 8595–8614

ESR1 dysfunction triggers neuroinflammation as a critical upstream causative factor of the Alzheimer’s disease process

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Figure 2.The bioinformatics analysis of the dataset GSE139549. (A) The heatmap and volcano plots representation of DEGs; (B) The interaction of DEGs between GSE139549 and HALLMARK enrichment derived from GSE153250; (C) Target gene-TF-miRNA network of the intersected DEGs between HALLMARK enrichment and GSE139549; (D) Co-expression of TF or genes in tissues of brain and nerve.