Research Paper Volume 14, Issue 20 pp 8498—8567

Figure 9. (A–H) Correlations between differentially expressed cadherin 1 (CDH1)/2/4/7/11/12/13/15 genes and immune cell infiltration in breast cancer. The figure showed that CDH1 (A); CDH2 (B); CDH4 (C); CDH7 (D); CDH11 (E); CDH12 (F); CDH13 (G); CDH15 (H) gene expressions were associated with tumor purity and tumor-infiltrating immune cell markers, such as cluster of differentiation 8-positive (CD8⁺) T cells, B cells, CD4⁺ T cells, neutrophils, macrophages, and dendritic cells. Spearman correlations were applied to describe correlations between the CDH1/2/4/7/11/12/13/15 genes and the abovementioned immune cells (p<0.05 was accepted as statistically significant).