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Research Paper Volume 14, Issue 20 pp 8302—8320

Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats

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Figure 7. Graphical abstract. Mitochondrial dysfunction occurs following AKI and may lead to apoptosis, which can be aggravated by obesity. TIIA can relieve apoptosis by improving mitochondrial function via activating PI3K/Akt/Bad pathway in obesity rats.