Research Paper Volume 14, Issue 20 pp 8302—8320

Figure 1. Tanshinone IIA (TIIA) improved the renal function, malondialdehyde (MDA), superoxide dismutase (SOD), inflammatory factor, and renal architecture after renal ischemia-reperfusion (IR). Rats were pre-treated with TIIA followed by removing the right kidney and clamping of the left renal artery for 30 min and reperfusion for 24 h. Sham rats were used as control. Renal function (A), MDA, SOD (B), inflammatory factor (C), and renal architecture (D) were evaluated under different groups. Representative photomicrographs of renal histology (D), the scale bars represent a length of 50 μm on histology, swollen renal tubules (paired yellow arrow). Data are shown as mean ± SD. *p < 0.05 versus sham group, ^#p < 0.05 versus IR (obese) group, ^∆p < 0.05 versus TIIA (5 mg/kg.d) group, ^▲p < 0.05 versus TIIA (10 mg/kg.d) group. (n=3).