Research Paper Volume 14, Issue 16 pp 6809—6828
LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis
Figure 6. H19 attenuated ERS-induced apoptosis and activated PI3K in HL-1 cells after HG. (A) Protein bands exposed the expression of p-PI3K, Nrf2, p-PERK, p-IRE1α, GRP 78 and GRP94 proteins in four cell groups. (B) Protein bands exposed the expression of CHOP, cleaved caspase-3, cleaved caspase-9, cleaved caspase-12, and BAX proteins in four cell groups, n = 3/group.