Research Paper Volume 14, Issue 16 pp 6626—6641
Oxypeucedanin relieves LPS-induced acute lung injury by inhibiting the inflammation and maintaining the integrity of the lung air-blood barrier
Figure 5. Potential mechanism of Oxypeucedanin in alleviating acute lung injury. OPD can significantly reduce LPS-induced acute lung injury inflammatory response and lung air-blood barrier dysfunction, and inhibited the activation of the PI3K/AKT, NF-κB, and MAPK signaling pathways, thus exerting a protective effect on acute lung injury.