Research Paper Volume 14, Issue 14 pp 5925—5945

miR-21 upregulation exacerbates pressure overload-induced cardiac hypertrophy in aged hearts

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Figure 7. High expression of circulating miR-21 in aged hypertensive subjects. (A) Circulating miR-21 expression in normotensive young, normotensive old, hypertensive young and hypertensive old subjects. (B) The linear correlation between intraventricular septal thickness at diastole (IVSd) and circulating miR-21 expression in hypertensive subjects. **P < 0.01 for difference from each group.