microRNA-497 prevents pancreatic cancer stem cell gemcitabine resistance, migration, and invasion by directly targeting nuclear factor kappa B 1

Qiangfeng Yu; Zhe Xiu; Yizeng Jian; Jianyin Zhou; Xiaopeng Chen; Xiang Chen; Chunxiang Chen; Hongbao Chen; Sijia Yang; Libo Yin; Wenlong Zeng

doi:doi:10.18632/aging.204193

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Research Paper Volume 14, Issue 14 pp 5908—5924

microRNA-497 prevents pancreatic cancer stem cell gemcitabine resistance, migration, and invasion by directly targeting nuclear factor kappa B 1

Figure 2. Gemcitabine resistance analysis of CSCs and non-CSCs from AsPC-1 and BxPC-3 cells. CSCs and non-CSCs from AsPC-1 and BxPC-3 cells were processed with different concentrations of gemcitabine for 24 h. Cell growth was determined with CCK-8 assay, and the IC50 values were calculated.