Research Paper Volume 14, Issue 19 pp 7774—7793
DNA methylation-regulated YTHDF2 correlates with cell migration and immune cell infiltration in glioma
Figure 7. YY1 activates YTHDF2 expression in glioma cells. (A) The expression of YY1in LGG tissues and normal tissues. (B) The prognosis of YY1 in TCGA-LGG was examined by GEPIA. (C) The expression of YY1 in diverse tumor grades of LGG examined by CGGA databases. (D) The expression of YY1 in diverse histology of in CGGA-LGG databases. (E) The ROC curve value of YY1 in TCGA-LGG. (F) YY1 expression was strongly positively associated with YTHDF1 expression in TCGA-LGG examined by GEPIA. (G) YY1 expression was strongly positively associated with YTHDF1 expression in LGG examined by CGGA. (H) The expression of YTHDF2 in U251 cells upon depletion of YY1 was examined by qRT-PCR assay.