Research Paper Volume 14, Issue 10 pp 4425—4444
Transcriptional ITPR3 as potential targets and biomarkers for human pancreatic cancer
Figure 8. ITPR3 is required for PAAD cell proliferation, migration, and invasion in vitro. (A) RT-qPCR analysis was employed to examine the efficiency of ITPR3 knockdown or overexpression in Bxpc3 and PANC1 cells. (B) Proliferation curves were determined in ITPR3 knockdown or overexpressed Bxpc3 and PANC1 cells by cell counting kit-8 (CCK-8) assays. (C) Clonogenic assays measured colony-forming abilities in ITPR3 stable knockdown or overexpressed Bxpc3 and PANC1 cells. (D) Transwell assays were used to detect the migration and invasive capacities in ITPR3 stable knockdown or overexpressed Bxpc3 and PANC1 cells.