Research Paper Volume 14, Issue 5 pp 2221—2238

Impact of the food grade heat-killed probiotic and postbiotic oral lozenges in oral hygiene

class="figure-viewer-img"

Figure 1. In vitro test for determining the antipathogenic activity of (A) individual postbiotic and (B) probiotic oral lozenges against oral pathogens. (A) Postbiotics of AP-32, ET-66, and LPL28 showed strong antibacterial activities compared with the positive control of LGG postbiotic. (B) Heat-killed AP-32 and ET-66 were used as inactivated probiotics, whereas metabolites of AP-32, ET-66, and LPL28 were used as postbiotics. *p < 0.05, **p < 0.01, and ***p < 0.001 compared with the positive control group (LGG postbiotic) or the placebo group (without the postbiotic). Data are presented as mean ± SD.