Research Paper Volume 14, Issue 3 pp 1307—1320
Inhibiting effect of miR-29 on proliferation and migration of uterine leiomyoma via the STAT3 signaling pathway
Figure 6. miR-29 inhibited proliferation in uterine leiomyoma cells (UtLMCs). (A) miR-29 mimics inhibited STAT-3, Cyclin D1, and c-Myc in vitro compared with the NC control, and MiR-29 inhibitors promoted the protein expression of STAT-3, Cyclin D1, and c-Myc in vitro compared with the anti-NC control. (B) miR-29 mimicking suppressed cell proliferation in UtLMCs in vitro compared with the NC control, and MiR-29 inhibitors promoted cell proliferation in UtLMCs in vitro compared with the anti-NC control. Data are presented as mean ± SE (*P < 0.05, **P < 0.01). UtLMCs: uterine leiomyoma cells; NC: negative control; STAT-3: signal transducer and activator of transcription 3.