Research Paper Volume 14, Issue 6 pp 2548—2557

Maslinic acid protects against pressure-overload-induced cardiac hypertrophy by blocking METTL3-mediated m6A methylation

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Figure 1. MA-mediated inhibition of the Ang-II induced NMCMs hypertrophy in vitro. (A) CCK-8 assay detection of the effect to MA on the cell viability of H9C2 and NMCMs; (B) Analysis of the effect of MA on the cardiomyocyte hypertrophy morphology after immune fluorescence staining with α-actinin and DAPI; (C) Quantitative analysis of cardiomyocyte surface area by image J software; *P<0.05, **P<0.01 compared to the indicated group.