Research Paper Volume 14, Issue 2 pp 678—707

Figure 1. KB1541 as a potential target for alleviating senescence. (A) The level of cellular proliferation was measured quantitatively using a DNA content-based method. ^**P < 0.01, Student's t-test. Mean ± S.D., n = 6. Chemical structure of an oxazoloquinoline derivative KB1541 was shown in rectangle. (B) Cell proliferation was assessed at different times (0–20 days) and concentrations of KB1541 (0–10 μM). ^**P < 0.01, two-way ANOVA followed by Bonferroni’s post test. Mean ± S.D., n = 10. (C) The toxicity of KB1541 at 4 μM concentration was examined by measuring cell viability. n.s. (not significant), two-way ANOVA followed by Bonferroni’s post test. Mean ± S.D., n = 3.