Research Paper Volume 13, Issue 22 pp 24882—24913

Figure 1. Systemic analysis of 26S proteasome delta subunit, non-ATPase (PSMD) family genes in 20 common types of cancer (Oncomine platform). Dysregulation of each PSMD individual gene in targeted cancer tissues as measured by the mRNA expression level was compared to their normal counterparts using Students’ t-test. The cutoff parameters were set as follows: p<0.05; multiple of change >2; and gene rank in the top 10%. The quantity of datasets which met those thresholds was represented as a number inside the table cells, while colors (red or blue) indicate the trend of gene expressions (up- or downregulation, respectively) and the intensity of colors indicates the degree of abnormal expression.