Research Paper Volume 13, Issue 22 pp 24815—24828

Figure 1. Illustration of the rat model of CSDH. (A) The sphenoid burr hole was made using a modified drill, and the dura was punctured under a microscope. (a) The microscopic photograph of the burr hole. (B) Prepare the cell-matrix glue mixture for injection. Representative photomicrograph of the morphology of bEnd.3 cells under light microscope and Sigma-Aldrich Matrigel. (C) A photograph of the entire assembly comprised of a stereotaxic frame and a stereotaxic injector with a 20-gauge catheter. (c) Zooming diagram of model rat. (D) Schematic diagram of drilled sphenoid burr hole, punctured dural hole, and catheter perfusion.