Construction and external validation of a 5-gene random forest model to diagnose non-obstructive azoospermia based on the single-cell RNA sequencing of testicular tissue

Ranran Zhou; Xianyuan Lv; Tianle Chen; Qi Chen; Hu Tian; Cheng Yang; Wenbin Guo; Cundong Liu

doi:doi:10.18632/aging.203675

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Research Paper Volume 13, Issue 21 pp 24219—24235

Construction and external validation of a 5-gene random forest model to diagnose non-obstructive azoospermia based on the single-cell RNA sequencing of testicular tissue

Figure 4. PPI network construction and functional enrichment. (A) Construction of a PPI network of the cell markers. (B) The Top 10 most important gene in the network. (C) KEGG pathway enrichment. (D) GO functional annotation. PPI, protein-protein interaction; KEGG, Kyoto Encyclopedia of Genes and Genomes; GO, Gene Ontology.