Figure 1. Elimination of inter-study bias in immune cell chip data. The batch effect correction of each chip was completed by the inSilicoMerging software package of Bioconductor. (A) Principal component analysis (PCA) analysis of each chip data before batch effect was removed; (B) PCA analysis of each chip data after the batch effect was removed; (C) The differential expression (|logFC|>1 and p<0.05) gene heat map of CD8 T cells and other immune cells.