Research Paper Volume 13, Issue 18 pp 22148—22163
Low expression of KIF20A suppresses cell proliferation, promotes chemosensitivity and is associated with better prognosis in HCC
Figure 8. Effects of KIF20A knockdown on the chemo-sensitivity of HCC cells. (A) Cell viability of si-NC or si-KIF20A-transfected HepG2 cells after treatment with different concentrations of cisplatin. (B) IC50 values of cisplatin in HepG2 cells transfected with si-NC or si-KIF20A. (C) Cell viability of si-NC or si-KIF20A-transfected SK-Hep1 cells after treatment with different concentrations of cisplatin. (D) IC50 values of cisplatin in SK-Hep1 cells transfected with si-NC or si-KIF20A. (E) Cell viability of si-NC or si-KIF20A-transfected HepG2 cells after treatment with different concentrations of sorafenib. (F) IC50 values of sorafenib in HepG2 cells transfected with si-NC or si-KIF20A. (G) Cell viability of si-NC or si-KIF20A-transfected SK-Hep1 cells after treatment with different concentrations of sorafenib. (H) IC50 values of sorafenib in SK-Hep1 cells transfected with si-NC or si-KIF20A. N = 3; *P<0.05, **P<0.01 and ***P<0.001.