Research Paper Volume 13, Issue 16 pp 20383—20394

Hsa_circ_0134111 promotes osteoarthritis progression by regulating miR-224-5p/CCL1 interaction

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Figure 2. Hsa_circ_0134111 knockdown alleviates IL-1β-induced apoptosis in chondrocytes. (A, B) Flow cytometric analysis of apoptosis. (CG) Representative western blot images and densitometric analysis of Bcl-2, cleaved caspase 3, aggrecan, and MMP13 expression in chondrocytes. **P<0.01, compared with control; ##P<0.01, compared with hsa_circ_0134111 siRNA1.