Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 13, Issue 4 pp 5967—5985
Transfer of lncRNA UCA1 by hUCMSCs-derived exosomes protects against hypoxia/reoxygenation injury through impairing miR-143-targeted degradation of Bcl-2
Figure 4. The hUCMSC-ex protects CMECs against autophagy following H/R injury. (A) Transmission electron microscope observation of autophagosomes; (B) Fluorescence localization of LC3 in CMECs under exposure to H/R injury. LC3 was labeled as green fluorescence, nucleus were labeled by DAPI and CMEC marker CD31 was labeled as red fluorescence. (C) LC3-II/LC3-I, Beclin-1 and p62 expression in CMECs under exposure to H/R injury measured by Western blot assay. *p < 0.05, vs. the control group; #p < 0.05, vs. the H/R or I/R group. All experiments were repeated 3 times. Data in panels (B and C) were analyzed with one-way ANOVA and Tukey’s multiple comparisons test.