Research Paper Volume 12, Issue 23 pp 24255—24269

Exploring the mechanism of resistance to sorafenib in two hepatocellular carcinoma cell lines

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Figure 2. Identification of differentially expressed genes (DEGs) in sorafenib resistance. (A) DEGs in sorafenib resistance. (B) Expression of sorafenib-targeted genes in sorafenib-sensitive and -resistant HepG2 cells. (C) Expression of sorafenib-targeted genes in sorafenib-sensitive and -resistant Huh7 cells. (D) Cluster heatmap of DEGs between sorafenib-sensitive and -resistant HepG2 cells. (E) Cluster heatmap between sorafenib-sensitive and -resistant Huh7 cells.