Figure 3. Heatmap of differentially expressed circular (circ)RNAs in distal cholangiocarcinoma. In total, 132 up- and 39 downregulated circRNAs were identified with microarray (|log2(fold change)|> 1 and p < 0.05). The green and yellow bars on the top represent tumor and normal tissues. In the middle, the color of boxes changes from red to blue, indicating high to low-expression of circRNAs. The first and second columns on the left represent classifications of circRNAs and the p-value of the differential analysis.