Research Paper Volume 12, Issue 16 pp 15995—16020

Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer’s disease: a pre-clinical study

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Figure 8. Treatment effects on brain anti- and pro-inflammatory cytokines. Detection of anti-inflammatory (panel A) and pro-inflammatory (panel B) cytokines by Western blot analysis in brain homogenates of 3xTg-AD mice (T0, C, LAB and p62-LAB groups). GAPDH was used as a control to check equal protein loading (*p<0.05 and ***p<0.001 vs T0, # p<0.05, ## p<0.01 and ###p<0.001 vs C, §§p<0.01 and §§§p<0.001 vs LAB).