Figure 6. Downregulation of circ_0072995 suppressed tumor growth in nude mice xenografts. (A) Representative images of tumor formation in xenografts of nude mice. (B) Tumor weight was suppressed after downregulation of circ_0072995 as measured 30 days post-injection. (C) Tumor volume was suppressed after downregulation of circ_0072995 as measured 30 days post-injection. (D) Expression of miR-147a was enhanced after downregulation circ_0072995 as determined by qRT-PCR. (E) The expression of CDK6 was suppressed after downregulation circ_0072995 as determined by qRT-PCR.