Figure 6.Knockdown of CD38 inhibits airway remodeling in asthmatic mice. (A, B) Immunohistochemistry analysis of CD38 protein expression in lung tissues. (C, D) Western blot analysis of CD38 protein expression in lung tissues (magnification: 400X). (E) Hemolysin staining of lung tissues (magnification: 400X). (F, G) Determination of ASM cell mass via immunohistochemistry staining of α-SMA (magnification: 400X). (H) Intracellular Ca2+ concentrations measured via Fluo-3 AM fluorescent probes in lung tissues. (I, J) Protein expression of total CREB an pCREB determined using Western blot. n = 3, *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001.
