Research Paper Volume 12, Issue 16 pp 16155—16171

RPP30, a transcriptional regulator, is a potential pathogenic factor in glioblastoma

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Figure 2. RPP30 involved in the post-translational modification in GBM and non-tumor brain samples. (A) Gene ontology (GO) analyses of RPP30 in GBM. Functional annotation of 500 genes most correlated to age in both CGGA and TCGA databases. (B) Gene ontology (GO) analyses of RPP30 in non-tumor brain samples. Functional annotation of 500 genes most correlated to age in GSE53890. (C) Correlation between RPP30 and GSVA scores of DNA, RNA, and Protein modification in CGGA, TCGA, and GSE53890. Red columns represented significant positive correlation. Blue columns represented significant negative correlation. Gray columns represent no significant correlation. The statistical significance was assessed by Pearson correlation analysis.