COVID-19 Review Volume 12, Issue 11 pp 10004—10021

From causes of aging to death from COVID-19

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Figure 4. Rejuvenating immunity by inhibiting hyperfunction. (A) Specific hyper-functional cells (or signaling pathways) can inhibit some other cell types (or pathways) that are needed for proper anti-viral response and immunization. (B) By inhibiting hyper-functional cells or pathways, rapamycin can reactivate “loss-of-function” otherwise suppressed by hyper-functional cells or pathways.