FAM83H and SCRIB stabilize β-catenin and stimulate progression of gastric carcinoma

Usama Khamis Hussein; Sang Hoon Ha; Asmaa Gamal Ahmed; Kyoung Min Kim; See-Hyoung Park; Chan Young Kim; Keun Sang Kwon; Zhongkai Zhang; Sang-A Lee; Ho Sung Park; Byung-Hyun Park; Ho Lee; Myoung Ja Chung; Woo Sung Moon; Myoung Jae Kang; Kyu Yun Jang

doi:doi:10.18632/aging.103351

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Research Paper Volume 12, Issue 12 pp 11812—11834

FAM83H and SCRIB stabilize β-catenin and stimulate progression of gastric carcinoma

Figure 3. Kaplan-Meier survival analysis according to co-expression patterns of nuclear FAM83H and nuclear SCRIB in gastric carcinoma patients. (A) Kaplan-Meier survival curves for overall survival and relapse-free survival in four subgroups of gastric carcinomas: FAM83H-N^-/SCRIB-N^-, FAM83H-N^-/SCRIB-N⁺, FAM83H-N⁺/SCRIB-N^-, and FAM83H-N⁺/SCRIB-N⁺ subgroups. (B) Kaplan-Meier survival curves for overall survival and relapse-free survival in three of gastric carcinomas: FAM83H^-/SCRIB-N^- or FAM83H-N^-/SCRIB-N⁺, FAM83H-N⁺/SCRIB-N^-, and FAM83H-N⁺/SCRIB-N⁺ subgroups. 5y-OS; overall survival rate at five years, 10y-OS; overall survival rate at ten years, 5y-RFS; relapse-free survival rate at five years, 10y-RFS; relapse-free survival rate at ten years.