Human amnion-derived mesenchymal stem cells promote osteogenic differentiation of human bone marrow mesenchymal stem cells via H19/miR-675/APC axis

Xiaojie Ma; Yifeng Bian; Hua Yuan; Ning Chen; Yongchu Pan; Weina Zhou; Shiyu Gao; Xin Du; Shushu Hao; Zixin Yan; Xuan Li; Keyue Liu; Fan Xu; Yuli Wang; Yifei Du

doi:doi:10.18632/aging.103277

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Research Paper Volume 12, Issue 11 pp 10527—10543

Human amnion-derived mesenchymal stem cells promote osteogenic differentiation of human bone marrow mesenchymal stem cells via H19/miR-675/APC axis

Figure 8. MiR-675 mimic could rescue the APC overexpression mediated inhibitory effects. (A) Relative mRNA expressions of ALP, RUNX2, OCN, and OSX were measured by RT-PCR analysis. (B) Alizarin red staining analysis. Scale bar, 1 cm. Data are shown as mean ± SD. **P < 0.01.