Research Paper Volume 12, Issue 11 pp 10517—10526
LncRNA SOCS2-AS1 inhibits progression and metastasis of colorectal cancer through stabilizing SOCS2 and sponging miR-1264
Figure 1. SOCS2-AS1 was downregulated in CRC. (A) Expression of SOCS2-AS1 in CRC and normal tissues according to TCGA data. GEPIA tool (http://gepia.cancer-pku.cn/detail.php) was used to analyze TCGA data. (B) Relative expression of SOCS2-AS1 in CRC and corresponding normal tissues was analyzed by qRT-PCR. (C) Analysis of SOCS2-AS1 level in CRC tissues and paired normal tissues by in situ hybridization (ISH). (D) Relative expression of SOCS2-AS1 in CRC cell lines. (E) Overall survival rate was plotted based on SOCS2-AS1 expression levels in CRC tissues. *P<0.05.