Figure 3 — Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone

Research Paper|Volume 12, Issue 10|pp. 9761–9780

Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone

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Figure 3.GH-deficiency alters absolute body composition parameters. Body composition parameters: BMD (C, D), BMC (E, F), lean mass (G, H) and fat mass (I, J) were measured by DXA. Female WT n=38, GHRH^-/- n=31, male WT n=16, GHRH^-/- n=14. Each bar represents mean. Statistical analysis was performed by unpaired Student’s t-test with Welch’s correction; ns= not significant, *p<0.05, ****p<0.0001.