Figure 6 — Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas

Research Paper|Volume 12, Issue 8|pp. 7183–7206

Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas

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Figure 6.Differential gene expression analysis. (A) Volcano plot showing the distribution of DEGs between KEAP1-mutated and wild-type LUAD patient samples based on significance and fold change. (B) Pie chart showing the percentages of overexpressed and underexpressed genes. (C) Heatmap showing the top DEGs between KEAP1-mutated and wild-type LUAD patient samples with Log Fc>|2| and p <0.05.