Research Paper Volume 12, Issue 6 pp 5280—5299

m6A-induced lncRNA MALAT1 aggravates renal fibrogenesis in obstructive nephropathy through the miR-145/FAK pathway

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Figure 1. MALAT1 expression was upregulated in renal fibrotic tissues in patients with ON. (A) HE analyses of kidney tissue with severe hydronephrosis from obstructive stones and normal tissue. (B) IHC analyses of α-SMA and ECM deposition in samples from patients with renal fibrosis. (C) qPCR analysis of MALAT1 expression in samples from patients with renal fibrosis].